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ImmunizationsStay protected with CDC-recommended vaccines including flu shots, COVID-19, shingles, and more.
Free DeliveryGet your prescriptions delivered to your home or office in Simpsonville for free.
Multi-Dose Pill Packaging (Compliance/Dispill)Simplify your health with $5 multi-dose pill packaging at Charlie's Hometown Pharmacy.
Medication Therapy Management (MTM)Personalized Medication Therapy Management to optimize your health and results.
Medication Adherence & Med SyncSync your prescriptions for a single monthly pickup and stay on track with your health.
Diabetes Care CenterManage your diabetes with expert guidance, local care, and personalized support.
Over The Counter & LEADER™ ProductsShop high-quality LEADER™ over the counter products and health essentials.
Prior Authorization AssistanceExpert help navigating insurance approvals for medications in Simpsonville.
Medicare Part D & Open EnrollmentExpert guidance on Medicare Part D and Open Enrollment.
Men's health and Erectile DysfunctionDiscreet and affordable Men's Health and Erectile Dysfunction solutions in Simpsonville.
Curbside PickupSave time with convenient curbside pickup. Get your prescriptions without leaving your car.
Cash Discount PlanSave money on prescriptions with our affordable Cash Discount Plan.
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About Us

Your Pharmacist, Your Neighbor

A Pharmacist Who Grew Up Here and Came Back to Serve

Charlie's Hometown Pharmacy is owned and operated by Charlie Brainard, RPh, PharmD, a lifelong Simpsonville resident and University of South Carolina graduate dedicated to serving his home community.

PharmD and RPh, University of South Carolina
Certified Immunization Pharmacist (CIP)
PCCA Hormone Replacement Therapy Specialist Certified
ACHC Accredited | NABP Member | HIPAA Certified | DEA Certified

Est. 2023

Serving Simpsonville since 2023.

1,000+ Patients

And growing every month.

Charlie Brainard, RPh, PharmD, owner and pharmacist at Charlie's Hometown Pharmacy in Simpsonville SC

Pharmacist providing personal care at Charlie's Hometown Pharmacy Simpsonville SC

Why Charlie's Hometown Pharmacy

What Makes Us Different

Hour-long waits, staff who don't know your name, and a pharmacist you've never met. Sound familiar? Charlie's Hometown Pharmacy is the independent pharmacy in Simpsonville, SC, built to be the opposite. No corporate red tape, no automated phone systems. Just a pharmacist who genuinely cares about this community.

01.

Same Pharmacist, Every Visit

Charlie Brainard, RPh, PharmD, is not a rotating face. He's here daily, a lifelong Simpsonville resident who personally reviews your prescriptions and always has time to talk.

02.

Prices That Match or Beat the Chains

Switching shouldn't cost you more. Charlie's prices match or beat chain pharmacy prices, and the pharmacy is a preferred provider with major insurance plans.

03.

Steps from Prisma Health Hillcrest Hospital

Located at 508 SE Main St, roughly 0.2 miles from Prisma Health Hillcrest Hospital. See your doctor and pick up your medications without crossing town.

Common Questions

What Patients Ask Us Most

New to Charlie's Hometown Pharmacy? Here are answers to the questions we hear most from patients in Simpsonville, Greenville, and Fountain Inn.

Have a question not listed here?

Talk to Your Pharmacist

(864) 665-5001

It's simple. Call us at (864) 665-5001 or use the Quick Rx app. Give us your current pharmacy details and we handle everything from there, contacting your old pharmacy, verifying insurance, and getting your medications ready, often the same day.

We accept all major insurance plans except Tricare. If you have questions about your specific coverage or need help with a prior authorization, Charlie can walk you through it in person or over the phone.

Yes. We offer free prescription delivery in the Simpsonville area. Same-day delivery may be available. Call us at (864) 665-5001 to confirm your address is within our delivery area.

Yes. Charlie is a Certified Immunization Pharmacist. We offer flu shots, COVID-19 vaccines, shingles, Tdap, pneumococcal, and more. Walk-ins are welcome for most immunizations.

We're at 508 SE Main St, Simpsonville, SC 29681, steps from Prisma Health Hillcrest Hospital. Open Monday through Friday 9:00 a.m. to 6:30 p.m., Saturday 10:00 a.m. to 3:00 p.m., and closed Sunday.

Ready to transfer your Rx?

Give us a call: (864) 665-5001

Pharmacy Hours

Mon-Fri: 09:00 AM - 6:30 PM, Sat: 10:00 AM - 3:00 PM, Sun: Closed

Explore Our Services

About Us

A Pharmacist Who Grew Up Here and Came Back to Serve

Est. 2023

1,000+ Patients